ICC/IF
AF488 staining on IF;Sample: Hela cellPrimary Ab: 30µg/ml Mouse Anti-Human SIRT1 AntibodySecond Ab: 2μg/ml AF488-Linked Caprine Anti-Mouse IgG Polyclonal Antibody| Product Name | Monoclonal Antibody to Sirtuin 1 (SIRT1) |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | RPE912Hu01-Recombinant Sirtuin 1 (SIRT1) |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2aKappa |
| Host Species | Mouse |
| Tested Applications | ICC/IF |
| ICC/IF: 5-20µg/mL |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Protein A/G |
| Gene Symbol | SIRT1 |
|---|---|
| Gene Synonyms | SIR2,SIR2L1,SIR2alpha |
| Gene Full Name | sirtuin 1 |
| Gene Summary | This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined,however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008] |
| Alternative Names | SIR2L1 Silent Mating Type Information Regulation 2 Homolog 1 NAD-Dependent Deacetylase Sirtuin-1 SIR2-like protein 1 SirtT1 75 kDa fragment |
ICC/IF
AF488 staining on IF;Sample: Hela cellPrimary Ab: 30µg/ml Mouse Anti-Human SIRT1 AntibodySecond Ab: 2μg/ml AF488-Linked Caprine Anti-Mouse IgG Polyclonal Antibody| Application Notes | ICC/IF: 5-20µg/mL |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles. |
| Storage Buffer | 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol. |
