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Monoclonal Antibody to Caspase 6 (CASP6)

Catalog Number:OM699640
Human
ICC/IF
OM699640
Discount Price
OM699640-100ul
100ul
Product Profile
Product Name Monoclonal Antibody to Caspase 6 (CASP6)
Antibody Type Primary Antibodies
Immunogen RPC340Hu01-Recombinant Caspase 6 (CASP6)
Key Feature
Clonality Monoclonal
Isotype IgG1Kappa
Host Species Mouse
Tested Applications ICC/IF
ICC/IF: 5-30µg/mL
Species Reactivity Human
Concentration 1mg/ml
Purification Protein A/G
Target Information
Gene Symbol CASP6
Gene Synonyms MCH2,CSP-6,caspase-6
Gene Full Name caspase 6
Gene Summary This gene encodes a member of the cysteine-aspartic acid protease (caspase) family of enzymes. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic acid residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Oct 2015]
Alternative Names MCH2
Cysteinyl Aspartate Specific Proteinases 6
Caspase 6
Apoptosis-Related Cysteine Peptidase
Apoptotic protease Mch-2
Application

ICC/IF

AF488 staining on IF;Sample: Hela cellPrimary Ab: 30µg/ml Mouse Anti-Human CASP6 AntibodySecond Ab: 2μg/ml AF488-Linked Caprine Anti-Mouse IgG Polyclonal Antibody
Application Notes ICC/IF: 5-30µg/mL
Additional Information
Form Liquid
Storage Instructions Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Storage Buffer 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
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