WB
Western Blot,Samples: Lane1: A549 cell lysate,Lane2: T-47D cell lysate,Lane3: Porcine Liver lysate,Primary Ab: 0.4µg/ml Mouse Anti-Human GHR Antibody Second Ab: 0.2μg/ml HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody| Product Name | Monoclonal Antibody to Growth Hormone Receptor (GHR) |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | RPB036Hu01-Recombinant Growth Hormone Receptor (GHR) |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1Kappa |
| Host Species | Mouse |
| Tested Applications | WB |
| WB: 0.01-2µg/mL |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Protein A/G |
| Gene Symbol | GHR |
|---|---|
| Gene Synonyms | GHBP,GHIP |
| Gene Full Name | growth hormone receptor |
| Gene Summary | This gene encodes a member of the type I cytokine receptor family, which is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature. In humans and rabbits, but not rodents, growth hormone binding protein (GHBP) is generated by proteolytic cleavage of the extracellular ligand-binding domain from the mature growth hormone receptor protein. Multiple alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jun 2011] |
| Alternative Names | GHBP Somatotropin receptor Growth hormone-binding protein Serum-binding protein |
WB
Western Blot,Samples: Lane1: A549 cell lysate,Lane2: T-47D cell lysate,Lane3: Porcine Liver lysate,Primary Ab: 0.4µg/ml Mouse Anti-Human GHR Antibody Second Ab: 0.2μg/ml HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody| Application Notes | WB: 0.01-2µg/mL |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles. |
| Storage Buffer | 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol. |
