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Monoclonal Antibody to Dystrophin (DMD)

Catalog Number:OM699700
Human
WB;ICC/IF
OM699700
Discount Price
OM699700-100ul
100ul
Product Profile
Product Name Monoclonal Antibody to Dystrophin (DMD)
Antibody Type Primary Antibodies
Immunogen RPB503Hu02-Recombinant Dystrophin (DMD)
Key Feature
Clonality Monoclonal
Isotype IgG1Kappa
Host Species Mouse
Tested Applications WBICC/IF
WB: 0.01-2µg/mL
ICC/IF:1:50-1:200
Species Reactivity Human
Concentration 1mg/ml
Purification Protein A/G
Target Information
Gene Symbol DMD
Gene Synonyms BMD,CMD3B,MRX85,DXS142,DXS164,DXS206,DXS230,DXS239,DXS268,DXS269,DXS270,DXS272
Gene Full Name dystrophin
Gene Summary This gene spans a genomic range of greater than 2 Mb and encodes a large protein containing an N-terminal actin-binding domain and multiple spectrin repeats. The encoded protein forms a component of the dystrophin-glycoprotein complex (DGC), which bridges the inner cytoskeleton and the extracellular matrix. Deletions, duplications, and point mutations at this gene locus may cause Duchenne muscular dystrophy (DMD), Becker muscular dystrophy (BMD), or cardiomyopathy. Alternative promoter usage and alternative splicing result in numerous distinct transcript variants and protein isoforms for this gene. [provided by RefSeq, Dec 2016]
Alternative Names CMD3B
Muscular Dystrophy
Duchenne And Becker Types
Application

ICC/IF

AF488 staining on IF;Sample: HepG2 cellPrimary Ab: 20µg/ml Mouse Anti-Human DMD AntibodySecond Ab: 2µg/ml AF488-Linked Caprine Anti-Mouse IgG Polyclonal Antibody

WB

Western Blot,Sample: Hela cell lysatePrimary Ab: 0.2µg/ml Mouse Anti-Human DMD AntibodySecond Ab: 0.2μg/ml HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody
Application Notes WB: 0.01-2µg/mL
ICC/IF:1:50-1:200
Additional Information
Form Liquid
Storage Instructions Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Storage Buffer PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
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