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Anti-IL7 antibody,pbs only

Catalog Number:ON661337
Human;Mouse;Rat
ELISA
ON661337
Discount Price
ON661337-100ul
100ul
Product Profile
Product Name Anti-IL7 antibody,pbs only
Antibody Type Primary Antibodies
Immunogen Polypeptide
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications ELISA
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol IL7
Gene Synonyms A630026I06Rik
CD127
CDW127
hlb368
IL-7
IL-7R-alpha
IL-7Ralpha
IL7RA
IL7Ralpha
ILRA
IMD104
IMD130
lnc-IL7R
sIL-7R
Gene Full Name interleukin 7
Gene Summary The protein encoded by this gene is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. IL7 is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRB) during early T cell development. This cytokine can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes. IL7 plays an essential role in lymphoid cell survival, and in the maintenance of naive and memory T cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their presence in normal tissues has not been confirmed. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection can be a potent inducer of proinflammatory cytokines and chemokines which may defend against the infection, but may also mediate destructive lung injury. Elevated serum IL7 levels, together with several other circulating cytokines and chemokines, has been found to be associated with the severity of Coronavirus Disease 19 (COVID-19). [provided by RefSeq, Jul 2020]
Alternative Names CD127 antigen
cytokine
H-IL-7
IL-7
IL-7 receptor alpha chain
IL-7 receptor subunit alpha
IL-7R subunit alpha
IL-7R-alpha
IL-7RA
IL7R
IL-7 receptor alpha chain
ILN
Interleukin
interleukin 7 precursor
interleukin 7 receptor alpha chain
interleukin-7 receptor precursor
Interleukin7
M-IL-7
soluble interleukin-7 receptor
Molecular Weight(MW) 20kDa
Cellular Localization Secreted
Database Links
SwissProt ID P13232
Application

ELISA

Coat the plate with immunizing antigen.Blue line: Immune serum; Orange line: Pre-immune serum.
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer PBS ONLY
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