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Anti-GRM8 antibody,pbs only

Catalog Number:ON661545
Human;Mouse;Rat
ELISA
ON661545
Discount Price
ON661545-100ul
100ul
Product Profile
Product Name Anti-GRM8 antibody,pbs only
Antibody Type Primary Antibodies
Immunogen Polypeptide
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications ELISA
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol GRM8
Gene Synonyms A230002O04
GLUR8
GPRC1H
mGlu8
mGlur
MGLUR8
mGluR8b
Gene Full Name glutamate metabotropic receptor 8
Gene Summary L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
Alternative Names FLJ41058
G protein coupled receptor
family C
group 1
member H
G protein-coupled receptor
family C
group 1
member H
G-protein coupled receptor
glutamate receptor
glutamate receptor
metabotropic 8
M mGlu8
metabotropic glutamate receptor subtype 8b
MGC126724
Molecular Weight(MW) 102kDa
Cellular Localization Cell membrane
Database Links
SwissProt ID O00222
Application

ELISA

Coat the plate with immunizing antigen.Blue line: Immune serum; Orange line: Pre-immune serum.
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer PBS ONLY
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