The protein encoded by this gene is a tetrodotoxin-resistant voltage-gated sodium channel alpha subunit. The properties of the channel formed by the encoded transmembrane protein can be altered by interaction with different beta subunits. This protein may be involved in the onset of pain associated with peripheral neuropathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]
Alternative Names
mPN3 NaV1.8 peripheral nerve sodium channel 3 SCN10A/PN3 sensory neuron sodium channel sodium channel protein type X subunit alpha sodium channel type X alpha polypeptide sodium channel voltage-gated type X alpha polypeptide sodium channel voltage-gated type 10 alpha polypeptide sodium channel voltage-gated type X alpha polypeptide sodium channel voltage-gated type X alpha subunit voltage gated sodium channel voltage gated sodium channel alpha subunit voltage-gated sodium channel subunit alpha Nav1.8