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Rabbit anti-TCF7L1 polyclonal antibody - N-terminal region

Catalog Number:OM105121
OM105121
Discount Price
OM105121-100ul
1~2 Week
100ul
OM105121-50ul
50ul
OM105121-20ul
20ul
1~2 Week
Product Profile
Product Name Rabbit anti-TCF7L1 polyclonal antibody - N-terminal region
Antibody Type Primary Antibodies
Antigen Alias TCF-3, TCF3
Immunogen The immunogen for anti-TCF7L1 antibody: synthetic peptide directed towards the N terminal of human TCF7L1
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WBIHC
WB:1:500~1:2000
IHC:1:50~1:200
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity Guinea PigHumanMouseRabbit
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol TCF7L1
Gene Synonyms TCF7L1
Gene Full Name Transcription factor 7-like 1 (T-cell specific, HMG-box)
Gene Summary TCF7L1 participates in the Wnt signaling pathway. It binds to DNA and acts as a repressor in the absence of CTNNB1, and as an activator in its presence. It is necessary for the terminal differentiation of epidermal cells, the formation of keratohyalin granules and the development of the barrier function of the epidermis. TCF7L1 down-regulates NQO1, leading to increased mitomycin c resistance.
Alternative Names TCF-3
TCF3
Molecular Weight(MW) 63kDa
Sequence 588 amino acids
Database Links
Entrez Gene 83439
SwissProt ID Q9HCS4
Protein Accession NP_112573
Application

Application

Immunohistochemistry with Human Skin lysate tissue at an antibody concentration of 5.0ug/ml using anti-TCF7L1 antibody ()

Application

WB Suggested Anti-TCF7L1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: 293T cell lysate
Application Notes WB:1:500~1:2000
IHC:1:50~1:200
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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