Western blot
Host: Rabbit Target Name: TRAF6 Sample Tissue: Human Adult Placenta Antibody Dilution: 1.0ug/mlWestern blot
Host: Rabbit Target Name: TRAF6 Sample Tissue: Human Fetal Liver Antibody Dilution: 1.0ug/mlWestern blot
0.2-1 ug/mlELISA Titer: 1:312500Positive Control: 293T cell lysateWestern blot
Host: Rabbit Target Name: TRAF6 Sample Tissue: Human Fetal Lung Antibody Dilution: 1.0ug/ml| Product Name | Rabbit anti-TRAF6 polyclonal antibody - middle region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MGC:3310, RNF85 |
| Immunogen | The immunogen for anti-TRAF6 antibody: synthetic peptide directed towards the middle region of human TRAF6 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | BovineDogHorseHumanMousePigRabbitRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | TRAF6 |
|---|---|
| Gene Synonyms | MGC:3310 RNF85 |
| Gene Full Name | TNF receptor-associated factor 6, E3 ubiquitin protein ligase |
| Gene Summary | TRAF6 is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. This protein mediates the signaling not only from the members of the TNF receptor superfamily, but also from the members of the Toll/IL-1 family. Signals from receptors such as CD40, TNFSF11/RANCE and IL-1 have been shown to be mediated by this protein. This protein also interacts with various protein kinases including IRAK1/IRAK, SRC and PKCzeta, which provides a link between distinct signaling pathways. This protein functions as a signal transducer in the NF-kappaB pathway that activates IkappaB kinase (IKK) in response to proinflammatory cytokines. The interaction of this protein with UBE2N/UBC13, and UBE2V1/UEV1A, which are ubiquitin conjugating enzymes catalyzing the formation of polyubiquitin chains, has been found to be required for IKK activation by this protein.The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. This protein mediates the signaling not only from the members of the TNF receptor superfamily, but also from the members of the Toll/IL-1 family. Signals from receptors such as CD40, TNFSF11/RANCE and IL-1 have been shown to be mediated by this protein. This protein also interacts with various protein kinases including IRAK1/IRAK, SRC and PKCzeta, which provides a link between distinct signaling pathways. This protein functions as a signal transducer in the NF-kappaB pathway that activates IkappaB kinase (IKK) in response to proinflammatory cytokines. The interaction of this protein with UBE2N/UBC13, and UBE2V1/UEV1A, which are ubiquitin conjugating enzymes catalyzing the formation of polyubiquitin chains, has been found to be required for IKK activation by this protein. Two alternatively spliced transcript variants encoding identical proteins have been reported. |
| Alternative Names | MGC:3310 RNF85 |
| Molecular Weight(MW) | 59kDa |
| Sequence | 522 amino acids |
Western blot
Host: Rabbit Target Name: TRAF6 Sample Tissue: Human Adult Placenta Antibody Dilution: 1.0ug/ml
Western blot
Host: Rabbit Target Name: TRAF6 Sample Tissue: Human Fetal Liver Antibody Dilution: 1.0ug/ml
Western blot
0.2-1 ug/mlELISA Titer: 1:312500Positive Control: 293T cell lysate
Western blot
Host: Rabbit Target Name: TRAF6 Sample Tissue: Human Fetal Lung Antibody Dilution: 1.0ug/ml| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
