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Rabbit anti-BAD polyclonal antibody - C-terminal region

Catalog Number:OM105183
OM105183
Discount Price
OM105183-100ul
1~2 Week
100ul
OM105183-50ul
50ul
OM105183-20ul
20ul
1~2 Week
Product Profile
Product Name Rabbit anti-BAD polyclonal antibody - C-terminal region
Antibody Type Primary Antibodies
Antigen Alias BBC2, BCL2L8
Immunogen The immunogen for anti-BAD antibody: synthetic peptide directed towards the C terminal of human BAD
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity BovineDogGuinea PigHorseHumanMousePigRabbitRat
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol BAD
Gene Synonyms BBC2
BCL2L8
Gene Full Name BCL2-associated agonist of cell death
Gene Summary BAD is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.
Alternative Names BBC2
BCL2L8
Molecular Weight(MW) 18kDa
Sequence 168 amino acids
Database Links
Entrez Gene 572
SwissProt ID Q92934
Protein Accession NP_004313
Application

Western blot

0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Human Live
Application Notes WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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