Western blot
0.2-1 ug/mlPositive Control: THP-1 cell lysate| Product Name | Rabbit anti-ARRB1 polyclonal antibody - middle region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ARB1, ARR1 |
| Immunogen | The immunogen for anti-ARRB1 antibody: synthetic peptide directed towards the middle region of human ARRB1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | BovineDogHorseHuman |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | ARRB1 |
|---|---|
| Gene Synonyms | ARB1 ARR1 |
| Gene Full Name | Arrestin, beta 1 |
| Gene Summary | Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described, however, their exact functions are not known. |
| Alternative Names | ARB1 ARR1 |
| Molecular Weight(MW) | 47kDa |
| Sequence | 418 amino acids |
Western blot
0.2-1 ug/mlPositive Control: THP-1 cell lysate| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
