Western blot
0.2-1 ug/mlELISA Titer: 1:12500Positive Control: ACHN cell lysate| Product Name | Rabbit anti-ESR1 polyclonal antibody - C-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | DKFZp686N23123, ER, ESR, ESRA, Era, NR3A1 |
| Immunogen | The immunogen for anti-ESR1 antibody: synthetic peptide directed towards the C terminal of human ESR1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | ESR1 |
|---|---|
| Gene Synonyms | DKFZp686N23123 ER ESR ESRA Era NR3A1 |
| Gene Full Name | Estrogen receptor 1 |
| Gene Summary | ESR1 is an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters. |
| Alternative Names | DKFZp686N23123 ER ESR ESRA Era NR3A1 |
| Molecular Weight(MW) | 66kDa |
| Sequence | 595 amino acids |
Western blot
0.2-1 ug/mlELISA Titer: 1:12500Positive Control: ACHN cell lysate| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
