Immunohistochemical
Human Optic Nerve and Spinal CordCellular Target: Oligoden Drocyte Lineage Cells Dilution: 1:500Western blot
OLIG2 antibody - N-terminal region validated by WB using human LCL and mouse brains at 1:1000.Western blot
0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Transfected 293T| Product Name | Rabbit anti-OLIG2 polyclonal antibody - N-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | BHLHB1, OLIGO2, PRKCBP2, RACK17, bHLHe19 |
| Immunogen | The immunogen for anti-OLIG2 antibody: synthetic peptide directed towards the N terminal of human OLIG2 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500~1:2000 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | Guinea PigHumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | OLIG2 |
|---|---|
| Gene Synonyms | BHLHB1 OLIGO2 PRKCBP2 RACK17 bHLHe19 |
| Gene Full Name | Oligodendrocyte lineage transcription factor 2 |
| Gene Summary | OLIG2 is a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. OLIG2 is an essential regulator of ventral neuroectodermal progenitor cell fate. It is associated with T-cell acute lymphoblastic leukemia due to a chromosomal translocation t(14;21)(q11.2;q22). OLIG2 might play a role in learning deficits associated with Down syndrome.This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14;21)(q11.2;q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
| Alternative Names | BHLHB1 OLIGO2 PRKCBP2 RACK17 bHLHe19 |
| Molecular Weight(MW) | 32kDa |
| Sequence | 323 amino acids |
Immunohistochemical
Human Optic Nerve and Spinal CordCellular Target: Oligoden Drocyte Lineage Cells Dilution: 1:500
Western blot
OLIG2 antibody - N-terminal region validated by WB using human LCL and mouse brains at 1:1000.
Western blot
0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Transfected 293T| Application Notes | WB:1:500~1:2000 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
