Western blot
0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: Human Muscle| Product Name | Rabbit anti-CREBL1 polyclonal antibody - middle region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CREB-RP, FLJ10066, G13, CREBL1 |
| Immunogen | The immunogen for anti-CREBL1 antibody: synthetic peptide directed towards the middle region of human CREBL1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | Pig |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | CREBL1 |
|---|---|
| Gene Synonyms | CREB-RP FLJ10066 G13 CREBL1 |
| Gene Full Name | Activating transcription factor 6 beta |
| Gene Summary | ATF6B(CREBL1) is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6-alpha, the protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. ATF6B is normally found in the membrane of the endoplasmic reticulum; however, under ER stress, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus. Two transcript variants encoding different isoforms have been found for this gene.The protein encoded by this gene bears sequence similarity with the Creb/ATF subfamily of the bZip superfamily of transcription factors. It localizes to both the cytoplasm and the nucleus. The gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
| Alternative Names | CREB-RP FLJ10066 G13 CREBL1 |
| Molecular Weight(MW) | 77kDa |
| Sequence | 703 amino acids |
Western blot
0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: Human Muscle| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
