Immunohistochemistry
Immunohistochemistry with Spleen tissue at an antibody concentration of 5ug/ml using anti-ETV5 antibodyWestern blot
0.2-1 ug/mlELISA Titer: 1:7812500Positive Control: Human Lung| Product Name | Rabbit anti-ETV5 polyclonal antibody - N-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ERM |
| Immunogen | The immunogen for anti-ETV5 antibody: synthetic peptide directed towards the N terminal of human ETV5 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | BovineDogGuinea PigHorseHumanMouseRabbitRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | ETV5 |
|---|---|
| Gene Synonyms | ERM |
| Gene Full Name | Ets variant 5 |
| Gene Summary | ETV5 Contains 1 ETS DNA-binding domain and belongs to the ETS family. The ETV5 gene expression is regulated by the conventional PKC (cPKC) pathway.ETV5 is subject to SUMO modification and this post-translational modification causes inhibition of transcription-enhancing activity Phosphorylated ETV5 and the actin cytoskeleton regulate CD44-mediated hyaluronan binding in myeloid cells. ERMs (ezrin/radixin/moesin) function as adaptor molecules in the interactions of adhesion receptors and intracellular tyrosine kinases. ETV5 can cooperate with c-Jun and has a role in progression of breast cancer. |
| Alternative Names | ERM |
| Molecular Weight(MW) | 58kDa |
| Sequence | 510 amino acids |
Immunohistochemistry
Immunohistochemistry with Spleen tissue at an antibody concentration of 5ug/ml using anti-ETV5 antibody
Western blot
0.2-1 ug/mlELISA Titer: 1:7812500Positive Control: Human Lung| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
