Western blot
5.0ug/ml| Product Name | MTF1 antibody - C-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | The immunogen for anti-MTF1 antibody: synthetic peptide directed towards the C terminal of human MTF1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| Species Reactivity | Bovine,Dog,Guinea Pig,Horse,Human,Mouse,Rabbit,Rat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | MTF1 |
|---|---|
| Gene Synonyms | ZRF MTF-1 |
| Gene Full Name | Metal-regulatory transcription factor 1 |
| Gene Summary | The zinc finger transcription factor MTF-1 (metal-responsive transcription factor-1) is conserved from insects to vertebrates. The major role of MTF-1 in both organisms is to control the transcription of genes involved in the homeostasis and detoxification of heavy metal ions such as Cu2+, Zn2+ and Cd2+. In mammals, MTF-1 serves at least two additional roles. First, targeted disruption of the MTF-1 gene results in death at embryonic day 14 due to liver degeneration, revealing a stage-specific developmental role. Second, under hypoxic-anoxic stress, MTF-1 helps to activate the transcription of the gene placental growth factor (PIGF), an angiogenic protein. |
| Alternative Names | ZRF MTF-1 |
| Molecular Weight(MW) | 81kDa |
| Sequence | 753 amino acids |
Western blot
5.0ug/ml| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
