Lanes :
Human placenta Primary Antibody Dilution : 1:200 Secondary Antibody :Anti-rabbit-HRP Secondary Antibody Dilution : 1:5000 Gene Name :Brown: EPAS1 Purple: Haemotoxylin Submitted by :EPAS1Western blot
0.2-1 ug/mlELISA Titer: 1:312500Positive Control: 293T cell lysate| Product Name | Rabbit anti-EPAS1 polyclonal antibody - middle region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | HIF2A, HLF, MOP2, PASD2, ECYT4, bHLHe73 |
| Immunogen | The immunogen for anti-EPAS1 antibody: synthetic peptide directed towards the middle region of human EPAS1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | BovineDogGuinea PigHorseHumanMousePigRabbitRatZebra Fish |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | EPAS1 |
|---|---|
| Gene Synonyms | HIF2A HLF MOP2 PASD2 ECYT4 bHLHe73 |
| Gene Full Name | Endothelial PAS domain protein 1 |
| Gene Summary | EPAS1 is a transcription factor involved in the induction of oxygen regulated genes. EPAS1 binds to core DNA sequence 5'-[AG]CGTG-3' within the hypoxia response element (HRE) of target gene promoters. EPAS1 regulates the vascular endothelial growth factor (VEGF) expression and seems to be implicated in the development of blood vessels and the tubular system of lung. EPAS1 may also play a role in the formation of the endothelium that gives rise to the blood brain barrier. EPAS1 is a potent activator of the Tie-2 tyrosine kinase expression. The activation seems to require recruitment of transcriptional coactivators such as CREBPB and probably EP300. Interaction of EPAS1 with redox regulatory protein APEX seems to activate CTAD. |
| Alternative Names | HIF2A HLF MOP2 PASD2 ECYT4 bHLHe73 |
| Molecular Weight(MW) | 90kDa |
| Sequence | 870 amino acids |
Lanes :
Human placenta Primary Antibody Dilution : 1:200 Secondary Antibody :Anti-rabbit-HRP Secondary Antibody Dilution : 1:5000 Gene Name :Brown: EPAS1 Purple: Haemotoxylin Submitted by :EPAS1
Western blot
0.2-1 ug/mlELISA Titer: 1:312500Positive Control: 293T cell lysate| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Data sheet for OM105698