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Rabbit anti-ESR2 polyclonal antibody - middle region

Catalog Number:OM105710
OM105710
Discount Price
OM105710-100ul
1~2 Week
100ul
OM105710-50ul
50ul
OM105710-20ul
20ul
1~2 Week
Product Profile
Product Name Rabbit anti-ESR2 polyclonal antibody - middle region
Antibody Type Primary Antibodies
Antigen Alias ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2
Immunogen The immunogen for anti-ESR2 antibody: synthetic peptide directed towards the middle region of human ESR2
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity BovineDogGuinea PigHumanMousePigRabbitRatSheep
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol ESR2
Gene Synonyms ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
Gene Full Name Estrogen receptor 2 (ER beta)
Gene Summary ESR2 is a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. It contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized.This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized.
Alternative Names ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
Molecular Weight(MW) 59kDa
Sequence 530 amino acids
Database Links
Entrez Gene 2100
SwissProt ID Q92731
Protein Accession NP_001428
Application

Western blot

Host: Rabbit Target Name: CHAD Sample Tissue: Human Adult Placenta Antibody Dilution: 1.0ug/ml
Application Notes WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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