Western blot
Host: Rabbit Target Name: RUVBL1 Sample Tissue: Human Fetal Lung Antibody Dilution: 1.0ug/mlWestern blot
Positive Control: Lane 1: 30ug K562 lysate Primary Antibody Dilution : 1:200Secondary Antibody : Anti-rabbit-HRP Secondry Antibody Dilution : 1:1000Submitted by: Sustackova Gabriela| Product Name | Rabbit anti-RUVBL1 polyclonal antibody - N-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ECP54, NMP238, Pontin52, RVB1, TIH1, TIP49, TIP49A, INO80H, PONTIN |
| Immunogen | The immunogen for anti-RUVBL1 antibody: synthetic peptide directed towards the N terminal of human RUVBL1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | BovineDogHorseHumanMouseRabbitZebra Fish |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | RUVBL1 |
|---|---|
| Gene Synonyms | ECP54 NMP238 Pontin52 RVB1 TIH1 TIP49 TIP49A INO80H PONTIN |
| Gene Full Name | RuvB-like 1 (E. coli) |
| Gene Summary | RUVBL1 possesses single-stranded DNA-stimulated ATPase and ATP-dependent DNA helicase (3' to 5') activity. It is the component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage. RUVBL1 plays an essential role in oncogenic transformation by MYC and also modulates transcriptional activation by the LEF1/TCF1-CTNNB1 complex. |
| Alternative Names | ECP54 NMP238 Pontin52 RVB1 TIH1 TIP49 TIP49A INO80H PONTIN |
| Molecular Weight(MW) | 50kDa |
| Sequence | 456 amino acids |
Western blot
Host: Rabbit Target Name: RUVBL1 Sample Tissue: Human Fetal Lung Antibody Dilution: 1.0ug/ml
Western blot
Positive Control: Lane 1: 30ug K562 lysate Primary Antibody Dilution : 1:200Secondary Antibody : Anti-rabbit-HRP Secondry Antibody Dilution : 1:1000Submitted by: Sustackova Gabriela| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
