Western blot
1.25ug/mlPositive Control: Human Thymus| Product Name | Rabbit anti-ASCL1 polyclonal antibody - N-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ASH1, HASH1, MASH1, bHLHa46 |
| Immunogen | The immunogen for anti-ASCL1 antibody: synthetic peptide directed towards the N terminal of human ASCL1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500~1:2000 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | BovineDogGuinea PigHumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | ASCL1 |
|---|---|
| Gene Synonyms | ASH1 HASH1 MASH1 bHLHa46 |
| Gene Full Name | Achaete-scute complex homolog 1 (Drosophila) |
| Gene Summary | ASCL1 encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. It is highly expressed in medullary thyroid cancer and small cell lung cancer and may be a useful marker for these cancers. |
| Alternative Names | ASH1 HASH1 MASH1 bHLHa46 |
| Molecular Weight(MW) | 25kDa |
| Sequence | 236 amino acids |
Western blot
1.25ug/mlPositive Control: Human Thymus| Application Notes | WB:1:500~1:2000 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
