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Rabbit anti-SIRT4 polyclonal antibody - middle region

Catalog Number:OM105817
OM105817
Discount Price
OM105817-100ul
1~2 Week
100ul
OM105817-50ul
50ul
OM105817-20ul
20ul
1~2 Week
Product Profile
Product Name Rabbit anti-SIRT4 polyclonal antibody - middle region
Antibody Type Primary Antibodies
Antigen Alias MGC130046, MGC130047, MGC57437, SIR2L4, sirtuin 4
Immunogen The immunogen for anti-SIRT4 antibody: synthetic peptide directed towards the middle region of human SIRT4
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WBIHC
WB:1:500~1:2000
IHC:1:50~1:200
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity BovineDogHumanMousePigRatSheep
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol SIRT4
Gene Synonyms MGC130046
MGC130047
MGC57437
SIR2L4
sirtuin 4
Gene Full Name Sirtuin 4
Gene Summary SIRT4 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. SIRT4 is included in class IV of the sirtuin family.This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family.
Alternative Names MGC130046
MGC130047
MGC57437
SIR2L4
sirtuin 4
Molecular Weight(MW) 35kDa
Sequence 314 amino acids
Database Links
Entrez Gene 23409
SwissProt ID Q9Y6E7
Protein Accession NP_036372
Application

Immunohistochemical

Pancreas

Western blot

0.2-1 ug/mlELISA Titer: 1:62500Positive Control: MCF7 cell lysate
Application Notes WB:1:500~1:2000
IHC:1:50~1:200
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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