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PPARG antibody - N-terminal region

Catalog Number:OM106077
OM106077
Discount Price
OM106077-100ul
1~2 Week
100ul
OM106077-50ul
50ul
OM106077-20ul
20ul
1~2 Week
Product Profile
Product Name PPARG antibody - N-terminal region
Antibody Type Primary Antibodies
Immunogen The immunogen for anti-PPARG antibody: synthetic peptide directed towards the N terminal of human PPARG
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
Species Reactivity Dog,Human,Pig
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol PPARG
Gene Synonyms NR1C3
PPARG1
PPARG2
GLM1
CIMT1
PPARgamma
Gene Full Name Peroxisome proliferator-activated receptor gamma
Gene Summary PPARG is a receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the receptor binds to a promoter element in the gene for acyl-CoA oxidase and activates its transcription. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. PPARG is the key regulator of adipocyte differentiation and glucose homeostasis.This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described.
Alternative Names NR1C3
PPARG1
PPARG2
GLM1
CIMT1
PPARgamma
Molecular Weight(MW) 57kDa
Sequence 505 amino acids
Database Links
Entrez Gene 5468
SwissProt ID P37231
Protein Accession NP_056953
Application

Western blot

0.2-1 ug/ml
ELISA Titer: 1:500
Positive Control: Jurkat cell lysate
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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