Immunohistochemistry
Immunohistochemistry with Spleen cell lysate tissue at an antibody concentration of 5.0ug/ml using anti-PML antibodyWestern blot
1 ug/ml| Product Name | PML antibody - C-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | The immunogen for anti-PML antibody: synthetic peptide directed towards the C terminal of human PML |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB,IHC |
| Species Reactivity | Bovine,Guinea Pig,Horse,Human,Mouse,Pig,Rat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | PML |
|---|---|
| Gene Synonyms | MYL PP8675 RNF71 TRIM19 |
| Gene Full Name | Promyelocytic leukemia |
| Gene Summary | PML is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. PML localizes to nuclear bodies where it functions as a transcription factor and tumor suppressor. Its expression is cell-cycle related and it regulates the p53 response to oncogenic signals. The gene is often involved in the translocation with the retinoic acid receptor alpha gene associated with acute promyelocytic leukemia (APL). Extensive alternative splicing of this gene results in several variations of the protein's central and C-terminal regions; all variants encode the same N-terminus. |
| Alternative Names | MYL PP8675 RNF71 TRIM19 |
| Molecular Weight(MW) | 59kDa |
| Sequence | 540 amino acids |
Immunohistochemistry
Immunohistochemistry with Spleen cell lysate tissue at an antibody concentration of 5.0ug/ml using anti-PML antibody
Western blot
1 ug/ml| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
