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ACTL6A antibody - N-terminal region

Catalog Number:OM106291
OM106291
Discount Price
OM106291-100ul
1~2 Week
100ul
OM106291-50ul
50ul
OM106291-20ul
20ul
1~2 Week
Product Profile
Product Name ACTL6A antibody - N-terminal region
Antibody Type Primary Antibodies
Immunogen The immunogen for anti-ACTL6A antibody: synthetic peptide directed towards the N terminal of human ACTL6A
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
Species Reactivity Bovine,Dog,Horse,Human,Mouse,Pig,Rabbit,Rat
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol ACTL6A
Gene Synonyms ACTL6
BAF53A
MGC5382
Arp4
INO80K
ARPN-BETA
Gene Full Name Actin-like 6A
Gene Summary This gene encodes a family member of actin-related proteins (ARPs), which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a 53 kDa subunit protein of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. Together with beta-actin, it is required for maximal ATPase activity of BRG1, and for the association of the BAF complex with chromatin/matrix. Three transcript variants that encode two different protein isoforms have been described.
Alternative Names ACTL6
BAF53A
MGC5382
Arp4
INO80K
ARPN-BETA
Molecular Weight(MW) 47kDa
Sequence 429 amino acids
Database Links
Entrez Gene 86
SwissProt ID O96019
Protein Accession NP_004292
Application

Immunoblot

1. Mouse WT brain extract (80ug) 2. Rat brain extract (80ug)
Primary Antibody Dilution:
2ug/ml
Secondary Antibody:
IRDye 800CW goat anti-rabbit from Li-COR Bioscience
Secondary Antibody Dilution:
1: 20,000
Gene Name:
ACTL6A
Submitted by:
Dr. Yuzhi Chen, University of Arkansas for Medical Science
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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