Western blot
0.2-1 ug/mlImmunohistochemistry
Immunohistochemistry with Placenta tissue at an antibody concentration of 5ug/ml using anti-ING3 antibody| Product Name | ING3 antibody - middle region |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | The immunogen for anti-ING3 antibody: synthetic peptide directed towards the middle region of human ING3 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| Species Reactivity | Bovine,Dog,Horse,Human,Mouse,Pig,Rabbit,Rat,Zebra Fish |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | ING3 |
|---|---|
| Gene Synonyms | Eaf4 FLJ20089 ING2 p47ING3 MEAF4 |
| Gene Full Name | Inhibitor of growth family, member 3 |
| Gene Summary | ING3 is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This gene can activate p53 trans-activated promoters, including promoters of p21/waf1 and bax. Overexpression of this gene has been shown to inhibit cell growth and induce apoptosis. Allelic loss and reduced expression of this gene were detected in head and neck cancers.The protein encoded by this gene is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This gene can activate p53 trans-activated promoters, including promoters of p21/waf1 and bax. Overexpression of this gene has been shown to inhibit cell growth and induce apoptosis. Allelic loss and reduced expression of this gene were detected in head and neck cancers. Two alternatively spliced transcript variants encoding different isoforms have been observed. |
| Alternative Names | Eaf4 FLJ20089 ING2 p47ING3 MEAF4 |
| Molecular Weight(MW) | 47kDa |
| Sequence | 418 amino acids |
Western blot
0.2-1 ug/ml
Immunohistochemistry
Immunohistochemistry with Placenta tissue at an antibody concentration of 5ug/ml using anti-ING3 antibody| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
