Rabbit anti-TP63 polyclonal antibody - N-terminal region

Name: Rabbit anti-TP63 polyclonal antibody - N-terminal region
Brand: Omnimabs
SKU: OM106629
Price: 130.00 USD
Availability: OutOfStock

Catalog Number：OM106629

Reactivity: Bovine;Dog;Horse;Human;Rabbit;Rat;Zebra Fish

Application: WB

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Product Profile

Product Name	Rabbit anti-TP63 polyclonal antibody - N-terminal region
Antibody Type	Primary Antibodies
Antigen Alias	RNF3, DONG1, RNF3A
Immunogen	The immunogen for anti-TP63 antibody: synthetic peptide directed towards the N terminal of human TP63

Key Feature

Clonality	Polyclonal
Isotype	IgG
Host Species	Rabbit
Tested Applications	WB
	WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity	BovineDogHorseHumanRabbitRatZebra Fish
Concentration	1mg/ml
Purification	Affinity purified

Target Information

Gene Symbol	TP63
Gene Synonyms	PCGF3
Gene Full Name	Tumor protein p63
Gene Summary	This protein plays in the development and maintenance of stratified epithelial tissues. p63 -/- mice have several developmental defects which include the lack of limbs and other tissues, such as teeth and mammary glands, which develop as a result of interactions between mesenchyme and epithelium. This gene encodes a member of the p53 family of transcription factors. An animal model, p63 -/- mice, has been useful in defining the role this protein plays in the development and maintenance of stratified epithelial tissues. p63 -/- mice have several developmental defects which include the lack of limbs and other tissues, such as teeth and mammary glands, which develop as a result of interactions between mesenchyme and epithelium. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3); split-hand/foot malformation 4 (SHFM4); ankyloblepharon-ectodermal defects-cleft lip/palate; ADULT syndrome (acro-dermato-ungual-lacrimal-tooth); limb-mammary syndrome; Rap-Hodgkin syndrome (RHS); and orofacial cleft 8. Both alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different proteins. Many transcripts encoding different proteins have been reported but the biological validity and the full-length nature of these variants have not been determined.
Alternative Names	RNF3 DONG1 RNF3A
Molecular Weight(MW)	77kDa
Sequence	680 amino acids

Database Links

Entrez Gene	8626
SwissProt ID	Q9H3D4
Protein Accession	NP_003713

Application

Application

Lanes: Lane 1: 50ug Hela LysatePrimary Antibody Dilution: 1:1000Secondary Antibody: Anti-rabbit-HRPSecondary Antibody Dilution: 1:10,000Gene Name: RBM14Submitted by: Archa Fox, University of Western Australia

Application

Application Notes	WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher.

Additional Information

Form	Liquid
Storage Instructions	Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer	phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

validation

Data sheet for OM106629

Rabbit anti-TP63 polyclonal antibody - N-terminal region

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