Western blot
0.2-1 ug/mlELISA Titer: 1:12500Positive Control: Human brainImmunohistochemical
Rat Hippocampal Neurons - 14DIVPrimary Antibody Dilution :1:200Secondary Antibody :Anti-rabbit-Cy3Secondary Antibody Dilution :1:500Color/Signal Descriptions :Green: GFP Red: NR2b Yellow: VGLUT12Gene Name :GRIN2BSubmitted by :Dan Fowler - University of Oregon, Institute of Neuroscience| Product Name | Rabbit anti-GRIN2B polyclonal antibody - middle region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MGC142178, MGC142180, NMDAR2B, NR2B, hNR3, MRD6, GluN2B |
| Immunogen | The immunogen for anti-GRIN2B antibody: synthetic peptide directed towards the middle region of human GRIN2B |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | BovineGuinea PigHorseHumanMousePigRabbitRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | GRIN2B |
|---|---|
| Gene Synonyms | MGC142178 MGC142180 NMDAR2B NR2B hNR3 MRD6 GluN2B |
| Gene Full Name | Glutamate receptor, ionotropic, N-methyl D-aspartate 2B |
| Gene Summary | GRIN2B is the NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium.N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA receptor channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of three different subunits: NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B). The NR2 subunit acts as the agonist binding site for glutamate. This receptor is the predominant excitatory neurotransmitter receptor in the mammalian brain. Sequence Note: This RefSeq was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-544 U90278.1 31-574 545-545 U88963.1 545-545 546-3677 U90278.1 576-3707 3678-5941 AC007535.3 145452-147715 |
| Alternative Names | MGC142178 MGC142180 NMDAR2B NR2B hNR3 MRD6 GluN2B |
| Molecular Weight(MW) | 163kDa |
| Sequence | 1484 amino acids |
Western blot
0.2-1 ug/mlELISA Titer: 1:12500Positive Control: Human brain
Immunohistochemical
Rat Hippocampal Neurons - 14DIVPrimary Antibody Dilution :1:200Secondary Antibody :Anti-rabbit-Cy3Secondary Antibody Dilution :1:500Color/Signal Descriptions :Green: GFP Red: NR2b Yellow: VGLUT12Gene Name :GRIN2BSubmitted by :Dan Fowler - University of Oregon, Institute of Neuroscience| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
