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Rabbit anti-P2RX1 polyclonal antibody - middle region

Catalog Number:OM107180
OM107180
Discount Price
OM107180-100ul
1~2 Week
100ul
OM107180-50ul
50ul
OM107180-20ul
20ul
1~2 Week
Product Profile
Product Name Rabbit anti-P2RX1 polyclonal antibody - middle region
Antibody Type Primary Antibodies
Antigen Alias P2X1
Immunogen The immunogen for anti-P2RX1 antibody: synthetic peptide directed towards the middle region of human P2RX1
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WBIHC
WB:1:500~1:2000
IHC:1:50~1:200
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity BovineDogGuinea PigHorseHumanMouseRabbitRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol P2RX1
Gene Synonyms P2RX1
Gene Full Name Purinergic receptor P2X, ligand-gated ion channel, 1
Gene Summary P2RX1 belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel with relatively high calcium permeability. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle, being responsible, for example, for sympathetic vasoconstriction in small arteries, arterioles and vas deferens. Mouse studies suggest that this receptor is essential for normal male reproductive function. It is possible that the development of selective antagonists for this receptor may provide an effective non-hormonal male contraceptive pill.The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel with relatively high calcium permeability. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle, being responsible, for example, for sympathetic vasoconstriction in small arteries, arterioles and vas deferens. Mouse studies suggest that this receptor is essential for normal male reproductive function. It is possible that the development of selective antagonists for this receptor may provide an effective non-hormonal male contraceptive pill.
Alternative Names P2X1
Molecular Weight(MW) 45kDa
Sequence 399 amino acids
Database Links
Entrez Gene 5023
SwissProt ID P51575
Protein Accession NP_002549
Application

Application

Human Pancreas

Application

WB Suggested Anti-P2RX1 Antibody Titration: 2.5ug/mlELISA Titer: 1:312500Positive Control: HepG2 cell lysate
Application Notes WB:1:500~1:2000
IHC:1:50~1:200
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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