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Rabbit anti-KLF6 polyclonal antibody - middle region

Catalog Number:OM107413
OM107413
Discount Price
OM107413-100ul
1~2 Week
100ul
OM107413-50ul
50ul
OM107413-20ul
20ul
1~2 Week
Product Profile
Product Name Rabbit anti-KLF6 polyclonal antibody - middle region
Antibody Type Primary Antibodies
Antigen Alias GBF, ZF9, BCD1, CBA1, CPBP, PAC1, ST12, COPEB
Immunogen The immunogen for anti-KLF6 antibody: synthetic peptide directed towards the middle region of human KLF6
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity DogHorseHumanMousePigRat
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol KLF6
Gene Synonyms GBF
ZF9
BCD1
CBA1
CPBP
PAC1
ST12
COPEB
Gene Full Name Kruppel-like factor 6
Gene Summary KLF6 is a nuclear protein that has three zinc fingers at the end of its C-terminal domain, a serine/threonine-rich central region, and an acidic domain lying within the N-terminal region. The zinc fingers of this protein are responsible for the specific DNA binding with the guanine-rich core promoter elements. The central region might be involved in activation or posttranslational regulatory pathways, and the acidic N-terminal domain might play an important role in the process of transcriptional activation. It is capable of activating transcription approximately 4-fold either on homologous or heterologous promoters. KLF6 may participate in the regulation and/or maintenance of the basal expression of pregnancy-specific glycoprotein genes and possibly other TATA box-less genes.This gene encodes a nuclear protein that has three zinc fingers at the end of its C-terminal domain, a serine/threonine-rich central region, and an acidic domain lying within the N-terminal region. The zinc fingers of this protein are responsible for the specific DNA binding with the guanine-rich core promoter elements. The central region might be involved in activation or posttranslational regulatory pathways, and the acidic N-terminal domain might play an important role in the process of transcriptional activation. It is capable of activating transcription approximately 4-fold either on homologous or heterologous promoters. The DNA binding and transcriptional activity of this protein, in conjunction with its expression pattern, suggests that this protein may participate in the regulation and/or maintenance of the basal expression of pregnancy-specific glycoprotein genes and possibly other TATA box-less genes. Two transcript variants encoding the same protein have been found for this gene.
Alternative Names GBF
ZF9
BCD1
CBA1
CPBP
PAC1
ST12
COPEB
Molecular Weight(MW) 32kDa
Sequence 283 amino acids
Database Links
Entrez Gene 1316
SwissProt ID Q99612
Protein Accession NP_001291
Application

Western blot

0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Transfected 293T
Application Notes WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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