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Rabbit anti-Elf3 polyclonal antibody - N-terminal region

Catalog Number:OM108008
OM108008
Discount Price
OM108008-100ul
1~2 Week
100ul
OM108008-50ul
50ul
OM108008-20ul
20ul
1~2 Week
Product Profile
Product Name Rabbit anti-Elf3 polyclonal antibody - N-terminal region
Antibody Type Primary Antibodies
Antigen Alias ESE-1, ESX, jen
Immunogen The immunogen for anti-Elf3 antibody: synthetic peptide directed towards the N terminal of mouse Elf3
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WBIHC
WB:1:500~1:2000
IHC:1:50~1:200
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity MouseRat
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol Elf3
Gene Synonyms Elf3
Gene Full Name E74-like factor 3
Gene Summary Elf3 is a transcriptional activator that binds and transactivates ETS sequences containing the consensus nucleotide core sequence GGA[AT]. It acts synergistically with POU2F3 to transactivate the SPRR2A promoter and with RUNX1 to transactivate the ANGPT1 promoter (By similarity). It also transactivates collagenase, CCL20, CLND7, FLG, KRT8, NOS2, PTGS2, SPRR2B, TGFBR2 and TGM3 promoters. IT represses KRT4 promoter activity (By similarity). It may play an important role in epithelial cell differentiation and tumorigenesis and may be a critical downstream effector of the ERBB2 signaling pathway (By similarity). It may be associated with mammary gland development and involution. It plays an important role in the regulation of transcription with TATA-less promoters in preimplantation embryos, which is essential in preimplantation development.
Alternative Names ESE-1
ESX
jen
Molecular Weight(MW) 41kDa
Sequence 371 amino acids
Database Links
Entrez Gene 13710
SwissProt ID Q3UPW2-2
Protein Accession NP_031947
Application

Application

Mouse Stomach

Application

WB Suggested Anti-Elf3 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Human Trachea
Application Notes WB:1:500~1:2000
IHC:1:50~1:200
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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