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Rabbit anti-Mafa polyclonal antibody - middle region

Catalog Number:OM108346
OM108346
Discount Price
OM108346-100ul
1~2 Week
100ul
OM108346-50ul
50ul
OM108346-20ul
20ul
1~2 Week
Product Profile
Product Name Rabbit anti-Mafa polyclonal antibody - middle region
Antibody Type Primary Antibodies
Antigen Alias RIPE3b1
Immunogen The immunogen for anti-Mafa antibody: synthetic peptide corresponding to a region of Mouse
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity MouseRat
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol Mafa
Gene Synonyms RIPE3b1
Gene Full Name V-maf musculoaponeurotic fibrosarcoma oncogene family, protein A (avian)
Gene Summary Mafa acts as a transcriptional factor. Mafa specifically binds the insulin enhancer element RIPE3b. Mafa cooperates synergistically with NEUROD1 and PDX1. Phosphorylation by GSK3 increases its transcriptional activity and is required for its oncogenic activity. Mafa regulates the insulin gene transcription. Mafa is involved either as an oncogene or as a tumor suppressor, depending on the cell context.
Alternative Names RIPE3b1
Molecular Weight(MW) 37kDa
Sequence 359 amino acids
Database Links
Entrez Gene 378435
SwissProt ID Q8CF90
Protein Accession NP_919331
Application

Western blot

0.2-1 ug/mlPositive Control: Mouse Kidney
Application Notes WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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