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Rabbit anti-MTA1 polyclonal antibody - middle region

Catalog Number:OM108393
OM108393
Discount Price
OM108393-100ul
1~2 Week
100ul
OM108393-50ul
50ul
OM108393-20ul
20ul
1~2 Week
Product Profile
Product Name Rabbit anti-MTA1 polyclonal antibody - middle region
Antibody Type Primary Antibodies
Immunogen The immunogen for anti-MTA1 antibody: synthetic peptide directed towards the middle region of human MTA1
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity BovineDogGuinea PigHumanMouseRabbitRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol MTA1
Gene Full Name Metastasis associated 1
Gene Summary MTA1 encodes a protein that was identified in a screen for genes expressed in metastatic cells, specifically, mammary adenocarcinoma cell lines. Expression of this gene has been correlated with the metastatic potential of at least two types of carcinomas although it is also expressed in many normal tissues. The role it plays in metastasis is unclear. MTA1 was initially thought to be the 70kD component of a nucleosome remodeling deacetylase complex, NuRD, but it is more likely that this component is a different but very similar protein. These two proteins are so closely related, though, that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. The profile and activity of this gene product suggest that it is involved in regulating transcription and that this may be accomplished by chromatin remodeling.
Molecular Weight(MW) 47kDa
Sequence 430 amino acids
Database Links
Entrez Gene 9112
SwissProt ID Q13330-2
Protein Accession AAN01613
Application

Western blot

2.5ug/mlELISA Titer: 1:312500Positive Control: Jurkat cell lysate
Application Notes WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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