Immunohistochemical
Western blot
0.2-1 ug/ml| Product Name | MAF antibody - N-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | The immunogen for anti-MAF antibody: synthetic peptide directed towards the N terminal of human MAF |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB,IHC |
| Species Reactivity | Bovine,Dog,Guinea Pig,Human,Mouse,Rat,Zebra Fish |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | MAF |
|---|---|
| Gene Synonyms | MGC71685 c-MAF |
| Gene Full Name | V-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian) |
| Gene Summary | MAF acts as a transcriptional activator or repressor. It is involved in embryonic lens fiber cell development. It recruits the transcriptional coactivators CREBBP and/or EP300 to crystallin promoters leading to up-regulation of crystallin gene during lens fiber cell differentiation. MAF is also involved in the initial chondrocyte terminal differentiation and the disappearance of hypertrophic chondrocytes during endochondral bone development. When overexpressed, MAF represses anti-oxidant reponse element (ARE)-mediated transcription. It may be involved either as an oncogene or as a tumor suppressor, depending on the cell context. |
| Alternative Names | MGC71685 c-MAF |
| Molecular Weight(MW) | 38kDa |
| Sequence | 373 amino acids |
| Entrez Gene | 4094 |
|---|---|
| SwissProt ID | O75444 |
| Protein Accession | NP_001026974 |
Immunohistochemical
Western blot
0.2-1 ug/ml| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
