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CARS antibody - C-terminal region

Catalog Number:OM109696
OM109696
Discount Price
OM109696-100ul
1~2 Week
100ul
OM109696-50ul
50ul
OM109696-20ul
20ul
1~2 Week
Product Profile
Product Name CARS antibody - C-terminal region
Antibody Type Primary Antibodies
Immunogen The immunogen for anti-CARS antibody: synthetic peptide directed towards the C terminal of human CARS
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB,IHC
Species Reactivity Bovine,Dog,Human,Mouse,Pig,Rabbit,Rat,Zebra Fish
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol CARS
Gene Synonyms CARS1
CYSRS
MGC:11246
Gene Full Name Cysteinyl-tRNA synthetase
Gene Summary CARS is a class 1 aminoacyl-tRNA synthetase, cysteinyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. This gene is one of several located near the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.This gene encodes a class 1 aminoacyl-tRNA synthetase, cysteinyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. This gene is one of several located near the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.
Alternative Names CARS1
CYSRS
MGC:11246
Molecular Weight(MW) 81kDa
Sequence 738 amino acids
Database Links
Entrez Gene 833
Protein Accession NP_001014438
Application

Western blot

0.2-1 ug/ml
Positive Control: HepG2 cell lysate
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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