| Product Name | Rabbit anti-RARA polyclonal antibody - N-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | NR1B1, RAR |
| Immunogen | The immunogen for anti-RARA antibody: synthetic peptide directed towards the N terminal of human RARA |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | RARA |
|---|---|
| Gene Synonyms | NR1B1 RAR |
| Gene Full Name | Retinoic acid receptor, alpha |
| Gene Summary | Retinoid signaling is transduced by 2 families of nuclear receptors, retinoic acid receptor (RAR) and retinoid X receptor, which form RXR/RAR heterodimers. In the absence of ligand, DNA-bound RXR/RARA represses transcription by recruiting the corepressors NCOR1, SMRT, and histone deacetylase. When ligand binds to the complex, it induces a conformational change allowing the recruitment of coactivators, histone acetyltransferases, and the basic transcription machinery. |
| Alternative Names | NR1B1 RAR |
| Molecular Weight(MW) | 51kDa |
| Sequence | 457 amino acids |
| Entrez Gene | 5914 |
|---|---|
| SwissProt ID | P10276-2 |
| Protein Accession | NP_001019980 |
| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
