Western blot
0.2-1 ug/mlPositive Control: HepG2 cell lysate| Product Name | Rabbit anti-ADAMTS4 polyclonal antibody - N-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ADAMTS-2, ADAMTS-4, ADMP-1, KIAA0688 |
| Immunogen | The immunogen for anti-ADAMTS4 antibody: synthetic peptide directed towards the N terminal of human ADAMTS4 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500~1:2000 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | BovineDogHorseHumanMousePig |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | ADAMTS4 |
|---|---|
| Gene Synonyms | ADAMTS-2 ADAMTS-4 ADMP-1 KIAA0688 |
| Gene Full Name | ADAM metallopeptidase with thrombospondin type 1 motif, 4 |
| Gene Summary | ADAMTS4 is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. ADAMTS4 lacks a C-terminal TS motif. It is responsible for the degradation of aggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellular matrix protein. The cleavage of aggrecan and brevican suggests key roles of this enzyme in arthritic disease and in the central nervous system, potentially, in the progression of glioma. |
| Alternative Names | ADAMTS-2 ADAMTS-4 ADMP-1 KIAA0688 |
| Molecular Weight(MW) | 37kDa |
| Sequence | 339 amino acids |
Western blot
0.2-1 ug/mlPositive Control: HepG2 cell lysate| Application Notes | WB:1:500~1:2000 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
