Western blot
Host: Rabbit Target Name: KIR3DL1 Sample Tissue: 293T Whole Cell lysates Antibody Dilution: 1.0ug/ml| Product Name | Rabbit anti-KIR3DL1 Antibody - middle region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CD158E1, KIR, KIR3DL1/S1, NKAT3, NKB1, NKB1B |
| Immunogen | The immunogen for Anti-KIR3DL1 antibody is: synthetic peptide directed towards the middle region of Human KIR3DL1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | KIR3DL1 |
|---|---|
| Gene Synonyms | CD158E1 KIR KIR3DL1/S1 NKAT3 NKB1 NKB1B |
| Gene Full Name | killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2 |
| Gene Summary | Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response. |
| Alternative Names | CD158E1 KIR KIR3DL1/S1 NKAT3 NKB1 NKB1B |
| Molecular Weight(MW) | 48kDa |
| Sequence | 444 amino acids |
Western blot
Host: Rabbit Target Name: KIR3DL1 Sample Tissue: 293T Whole Cell lysates Antibody Dilution: 1.0ug/ml| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
