Western blot
2.5ug/mlPositive Control: Jurkat cell lysate| Product Name | IRF6 antibody - C-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | The immunogen for anti-IRF6 antibody: synthetic peptide directed towards the C terminal of human IRF6 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| Species Reactivity | BovineDogHorseHumanMousePigRabbitRatSheep |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | IRF6 |
|---|---|
| Gene Synonyms | LPS OFC6 PIT PPS VWS VWS1 |
| Gene Full Name | Interferon regulatory factor 6 |
| Gene Summary | IRF6 is a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. Mutations in its gene can cause van der Woude syndrome and popliteal pterygium syndrome. This protein is involved in palate formation.The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eucaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction. |
| Alternative Names | LPS OFC6 PIT PPS VWS VWS1 |
| Molecular Weight(MW) | 65kDa |
| Sequence | 591 amino acids |
Western blot
2.5ug/mlPositive Control: Jurkat cell lysate| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
