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Rabbit anti-CPB2 polyclonal antibody - middle region

Catalog Number:OM111405
OM111405
Discount Price
OM111405-100ul
1~2 Week
100ul
OM111405-50ul
50ul
OM111405-20ul
20ul
1~2 Week
Product Profile
Product Name Rabbit anti-CPB2 polyclonal antibody - middle region
Antibody Type Primary Antibodies
Antigen Alias CPU, PCPB, TAFI
Immunogen The immunogen for anti-CPB2 antibody: synthetic peptide directed towards the middle region of human CPB2
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity DogHumanPig
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol CPB2
Gene Synonyms CPU
PCPB
TAFI
Gene Full Name Carboxypeptidase B2 (plasma)
Gene Summary Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). CPB2 is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). The protein encoded by this gene is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Polymorphisms have been described for this gene and its promoter region. Available sequence data analyses indicate splice variants that encode different isoforms.
Alternative Names CPU
PCPB
TAFI
Molecular Weight(MW) 36kDa
Sequence 423 amino acids
Database Links
Entrez Gene 1361
SwissProt ID Q96IY4
Protein Accession NP_001863
Application

Western blot

0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: Human heart
Application Notes WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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