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Rabbit anti-EPOR polyclonal antibody - N-terminal region

Catalog Number:OM111679
OM111679
Discount Price
OM111679-100ul
1~2 Week
100ul
OM111679-50ul
50ul
OM111679-20ul
20ul
1~2 Week
Product Profile
Product Name Rabbit anti-EPOR polyclonal antibody - N-terminal region
Antibody Type Primary Antibodies
Antigen Alias MGC138358, EPO-R
Immunogen The immunogen for anti-EPOR antibody: synthetic peptide directed towards the N terminal of human EPOR
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity BovineDogGuinea PigHorseHumanMousePigRat
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol EPOR
Gene Synonyms MGC138358
EPO-R
Gene Full Name Erythropoietin receptor
Gene Summary The erythropoietin receptor is a member of the cytokine receptor family. Upon erythropoietin binding, the erythropoietin receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis.The erythropoietin receptor is a member of the cytokine receptor family. Upon erythropoietin binding, the erythropoietin receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alternative Names MGC138358
EPO-R
Molecular Weight(MW) 53kDa
Sequence 508 amino acids
Database Links
Entrez Gene 2057
SwissProt ID P19235
Protein Accession NP_000112
Application

Western blot

0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: Human brain
Application Notes WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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