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Rabbit anti-MTHFD2 polyclonal antibody - N-terminal region

Catalog Number:OM112427
OM112427
Discount Price
OM112427-100ul
1~2 Week
100ul
OM112427-50ul
50ul
OM112427-20ul
20ul
1~2 Week
Product Profile
Product Name Rabbit anti-MTHFD2 polyclonal antibody - N-terminal region
Antibody Type Primary Antibodies
Antigen Alias NMDMC
Immunogen The immunogen for anti-MTHFD2 antibody: synthetic peptide directed towards the N terminal of human MTHFD2
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity DogGuinea PigHorseHumanMouseRat
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol MTHFD2
Gene Synonyms NMDMC
Gene Full Name Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
Gene Summary MTHFD2 is a nuclear-encoded mitochondrial bifunctional enzyme with methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities. The enzyme functions as a homodimer and is unique in its absolute requirement for magnesium and inorganic phosphate. Formation of the enzyme-magnesium complex allows binding of NAD.This gene encodes a nuclear-encoded mitochondrial bifunctional enzyme with methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities. The enzyme functions as a homodimer and is unique in its absolute requirement for magnesium and inorganic phosphate. Formation of the enzyme-magnesium complex allows binding of NAD. Alternative splicing results in multiple transcripts encoding different isoforms. This gene has a pseudogene on chromosome 7.
Alternative Names NMDMC
Molecular Weight(MW) 35kDa
Sequence 350 amino acids
Database Links
Entrez Gene 10797
SwissProt ID P13995
Protein Accession NP_006627
Application

Western blot

0.2-1 ug/mlELISA Titer: 1:312500Positive Control: 293T cell lysate
Application Notes WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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