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Rabbit anti-RNF213 Antibody - N-terminal region

Catalog Number:OM112968
OM112968
Discount Price
OM112968-100ul
1~2 Week
100ul
OM112968-50ul
50ul
OM112968-20ul
20ul
1~2 Week
Product Profile
Product Name Rabbit anti-RNF213 Antibody - N-terminal region
Antibody Type Primary Antibodies
Immunogen The immunogen for Anti-RNF213 antibody is: synthetic peptide directed towards the N-terminal region of Human RNF213
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity Human
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol RNF213
Gene Synonyms -
Gene Full Name ring finger protein 213
Gene Summary This gene encodes a protein containing a C3HC4-type RING finger domain, which is a specialized type of Zn-finger that binds two atoms of zinc and is thought to be involved in mediating protein-protein interactions. The protein also contains an AAA domain, which is associated with ATPase activity. This gene is a susceptibility gene for Moyamoya disease, a vascular disorder of intracranial arteries. This gene is also a translocation partner in anaplastic large cell lymphoma and inflammatory myofibroblastic tumor cases, where a t(2;17)(p23;q25) translocation has been identified with the anaplastic lymphoma kinase (ALK) gene on chromosome 2, and a t(8;17)(q24;q25) translocation has been identified with the MYC gene on chromosome 8.
Molecular Weight(MW) 118kDa,590kDa
Sequence 1063 amino acids
Database Links
Entrez Gene 57674
SwissProt ID Q63HN8-5
Protein Accession NP_066005
Application

Western blot

Host: Rabbit Target Name: RNF213 Sample Tissue: Thyroid Tumor lysates Antibody Dilution: 1.0ug/ml

WB

Relative expression in western blot: Antibody specificity was demonstrated by detection of known differential basal expression of the target across tissue/cell models. expression of RNF213 was observed specifically in A-549 cells and in HEK293 cells using anti-RNF213 Polyclonal Antibody in western blot.
Application Notes WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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