Western blot
5.0ug/mlPositive Control: Jurkat cell lysate| Product Name | Rabbit anti-CRYAB polyclonal antibody - C-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CRYA2, CTPP2, HSPB5 |
| Immunogen | The immunogen for anti-CRYAB antibody: synthetic peptide directed towards the C terminal of human CRYAB |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | BovineDogGuinea PigHumanMousePigRabbitRatSheep |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | CRYAB |
|---|---|
| Gene Synonyms | CRYA2 CTPP2 HSPB5 |
| Gene Full Name | Crystallin, alpha B |
| Gene Summary | Alpha crystallins are composed of: alpha-A and alpha-B, for acidic and basic, respectively. They act as molecular chaperones although they do not renature proteins and release them in the fashion of a true chaperone; instead they hold them in large soluble aggregates. Post-translational modifications decrease the ability to chaperone. Two additional functions of alpha crystallins are an autokinase activity and participation in the intracellular architecture. Alpha-A and alpha-B are differentially expressed; alpha-A is preferentially restricted to the lens and alpha-B is expressed widely in many tissues and organs. Elevated expression of alpha-B crystallin occurs in many neurological diseases; a missense mutation cosegregated in a family with a desmin-related myopathy. |
| Alternative Names | CRYA2 CTPP2 HSPB5 |
| Molecular Weight(MW) | 20kDa |
| Sequence | 175 amino acids |
Western blot
5.0ug/mlPositive Control: Jurkat cell lysate| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
