Chromatin Immunoprecipitation
Chromatin Immunoprecipitation (ChIP) Using Suv420h1 antibody - C-terminal region and HCT116 CellsWestern blot
Titration: 1.0 ug/mlPositive Control: Mouse Thymus| Product Name | Rabbit anti-Suv420h1 polyclonal antibody - C-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | AA117471, C630029K18Rik, KMT5B, MGC18702, Suv4-20h1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | DogHorseHumanRabbitRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | Suv420h1 |
|---|---|
| Gene Synonyms | AA117471 C630029K18Rik KMT5B MGC18702 Suv4-20h1 |
| Gene Full Name | Suppressor of variegation 4-20 homolog 1 (Drosophila) |
| Gene Summary | Suv420h1 is a histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. It mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. SUV420H1 is targeted to histone H3 via its interaction with RB1 family proteins. |
| Alternative Names | AA117471 C630029K18Rik KMT5B MGC18702 Suv4-20h1 |
| Molecular Weight(MW) | 35kDa |
| Sequence | 327 amino acids |
| Entrez Gene | 225888 |
|---|---|
| SwissProt ID | Q3U8K7-4 |
| Protein Accession | NP_001161356 |
Chromatin Immunoprecipitation
Chromatin Immunoprecipitation (ChIP) Using Suv420h1 antibody - C-terminal region and HCT116 Cells
Western blot
Titration: 1.0 ug/mlPositive Control: Mouse Thymus| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
