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Rabbit anti-PARK7 polyclonal antibody - C-terminal region

Catalog Number:OM114385
OM114385
Discount Price
OM114385-100ul
1~2 Week
100ul
OM114385-50ul
50ul
OM114385-20ul
20ul
1~2 Week
Product Profile
Product Name Rabbit anti-PARK7 polyclonal antibody - C-terminal region
Antibody Type Primary Antibodies
Antigen Alias DJ-1, DJ1, FLJ27376
Immunogen The immunogen for anti-PARK7 antibody: synthetic peptide directed towards the C terminal of human PARK7
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WBIHC
WB:1:500~1:2000
IHC:1:50~1:200
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity BovineDogHumanMousePigRat
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol PARK7
Gene Synonyms DJ-1
DJ1
FLJ27376
Gene Full Name Parkinson protein 7
Gene Summary PARK7 belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7.The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for this gene.
Alternative Names DJ-1
DJ1
FLJ27376
Molecular Weight(MW) 20kDa
Sequence 189 amino acids
Database Links
Entrez Gene 11315
SwissProt ID Q99497
Protein Accession NP_009193
Application

Immunofluorescence

Sample Type: Mouse Brain Slices Red: primaryBlue: DAPIPrimary Dilution: 1:400 Secondary Antibody: Anti-Rabbit IgG Alexa 594Secondary Dilution: 1:400 Image Submitted By: Adahir Labrador-Garrido and Cintia Roodveldt University of Seville

Western blot

PARK7 antibody - C-terminal region validated by WB using SH-SY5Y cell line at 1: 500.
Application Notes WB:1:500~1:2000
IHC:1:50~1:200
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
validation
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