Western blot
0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Human kidney| Product Name | Rabbit anti-CYP3A4 polyclonal antibody - middle region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CP33, CP34, CYP3A, CYP3A3, HLP, MGC126680, NF-25, P450C3, P450PCN1, CYPIIIA3, CYPIIIA4 |
| Immunogen | The immunogen for anti-CYP3A4 antibody: synthetic peptide directed towards the middle region of human CYP3A4 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | BovineHumanPig |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | CYP3A4 |
|---|---|
| Gene Synonyms | CP33 CP34 CYP3A CYP3A3 HLP MGC126680 NF-25 P450C3 P450PCN1 CYPIIIA3 CYPIIIA4 |
| Gene Full Name | Cytochrome P450, family 3, subfamily A, polypeptide 4 |
| Gene Summary | This gene, CYP3A4, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs which are are used today, including acetaminophen, codeine, cyclosporin A, diazepam and erythromycin. The enzyme also metabolizes some steroids and carcinogens. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Previously another CYP3A gene, CYP3A3, was thought to exist; however, it is now thought that this sequence represents a transcript variant of CYP3A4. |
| Alternative Names | CP33 CP34 CYP3A CYP3A3 HLP MGC126680 NF-25 P450C3 P450PCN1 CYPIIIA3 CYPIIIA4 |
| Molecular Weight(MW) | 57kDa |
| Sequence | 503 amino acids |
Western blot
0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Human kidney| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
