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Rabbit anti-TOB1 polyclonal antibody - middle region

Catalog Number:OM114681
OM114681
Discount Price
OM114681-100ul
1~2 Week
100ul
OM114681-50ul
50ul
OM114681-20ul
20ul
1~2 Week
Product Profile
Product Name Rabbit anti-TOB1 polyclonal antibody - middle region
Antibody Type Primary Antibodies
Antigen Alias APRO6, MGC104792, MGC34446, PIG49, TOB, TROB, TROB1
Immunogen The immunogen for anti-TOB1 antibody: synthetic peptide directed towards the middle region of human TOB1
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity BovineDogHorseHumanMousePigRat
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol TOB1
Gene Synonyms APRO6
MGC104792
MGC34446
PIG49
TOB
TROB
TROB1
Gene Full Name Transducer of ERBB2, 1
Gene Summary This gene encodes a member of the tob/btg1 family of anti-proliferative proteins that have the potential to regulate cell growth. When exogenously expressed, this protein supresses cell growth in tissue culture. The protein undergoes phophorylation by a serine/threonine kinase, 90 kDa ribosomal S6 kinase. Interactions of this protein with the v-erb-b2 erythroblastic leukemia viral oncogene homolog 2 gene product p185 interferes with growth suppression. This protein inhibits T cell proliferation and transcription of cytokines and cyclins. The protein interacts with both mothers against decapentaplegic Drosophila homolog 2 and 4 to enhance their DNA binding activity. This interaction inhibits interleukin 2 transcription in T cells.
Alternative Names APRO6
MGC104792
MGC34446
PIG49
TOB
TROB
TROB1
Molecular Weight(MW) 38kDa
Sequence 345 amino acids
Database Links
Entrez Gene 10140
SwissProt ID P50616
Protein Accession NP_005740
Application

Western blot

0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: Jurkat cell lysate
Application Notes WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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