Western blot
Titration: 1.0 ug/mlPositive Control: Mouse Spleen| Product Name | Rabbit anti-Katna1 polyclonal antibody - C-terminal region |
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| Antibody Type | Primary Antibodies |
| Immunogen | The immunogen for anti-Katna1 antibody: synthetic peptide corresponding to a region of Mouse |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
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| Species Reactivity | BovineDogHorseHumanMousePigRabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | Katna1 |
|---|---|
| Gene Synonyms | - |
| Gene Full Name | Katanin p60 (ATPase-containing) subunit A1 |
| Gene Summary | Katna1 severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays, such as that seen during disassembly of interphase microtubules at the G2-M transition.It may also be required for microtubule release from the centrosome after nucleation. In mitotic spindles this could allow depolymerization of the microtubule end proximal to the centrosome, and subsequent poleward microtubule flux. In neurons, microtubule release within the cell body allows their subsequent transport into neuronal processes by microtubule dependent motor proteins. This transport is required for axonal growth. |
| Molecular Weight(MW) | 54kDa |
| Sequence | 491 amino acids |
Western blot
Titration: 1.0 ug/mlPositive Control: Mouse Spleen| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
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| Form | Liquid |
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| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
