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Rabbit anti-PACRG polyclonal antibody - middle region

Catalog Number:OM115075
OM115075
Discount Price
OM115075-100ul
1~2 Week
100ul
OM115075-50ul
50ul
OM115075-20ul
20ul
1~2 Week
Product Profile
Product Name Rabbit anti-PACRG polyclonal antibody - middle region
Antibody Type Primary Antibodies
Antigen Alias FLJ32724, GLUP, HAK005771, PARK2CRG, RP3-495O10.2
Immunogen The immunogen for anti-PACRG antibody: synthetic peptide directed towards the middle region of human PACRG
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity BovineGuinea PigHumanMouseRatZebra Fish
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol PACRG
Gene Synonyms FLJ32724
GLUP
HAK005771
PARK2CRG
RP3-495O10.2
Gene Full Name PARK2 co-regulated
Gene Summary PACRG is a protein that is conserved across metazoans. In vertebrates, this gene is linked in a head-to-head arrangement with the adjacent parkin gene, which is associated with autosomal recessive juvenile Parkinson's disease. These genes are co-regulated in various tissues and they share a bi-directional promoter. Both genes are associated with susceptibility to leprosy. The parkin co-regulated gene protein forms a large molecular complex with chaperones, including heat shock proteins 70 and 90, and chaperonin components. This protein is also a component of Lewy bodies in Parkinson's disease patients, and it suppresses unfolded Pael receptor-induced neuronal cell death.This gene encodes a protein that is conserved across metazoans. In vertebrates, this gene is linked in a head-to-head arrangement with the adjacent parkin gene, which is associated with autosomal recessive juvenile Parkinson's disease. These genes are co-regulated in various tissues and they share a bi-directional promoter. Both genes are associated with susceptibility to leprosy. The parkin co-regulated gene protein forms a large molecular complex with chaperones, including heat shock proteins 70 and 90, and chaperonin components. This protein is also a component of Lewy bodies in Parkinson's disease patients, and it suppresses unfolded Pael receptor-induced neuronal cell death. Multiple transcript variants encoding different isoforms have been found for this gene.
Alternative Names FLJ32724
GLUP
HAK005771
PARK2CRG
RP3-495O10.2
Molecular Weight(MW) 33kDa
Sequence 296 amino acids
Database Links
Entrez Gene 135138
SwissProt ID Q96M98
Protein Accession NP_689623
Application

Western blot

0.2-1 ug/mlELISA Titer: 1:312500Positive Control: 293T cell lysate
Application Notes WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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