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Rabbit anti-GSN polyclonal antibody - C-terminal region

Catalog Number:OM115559
OM115559
Discount Price
OM115559-100ul
1~2 Week
100ul
OM115559-50ul
50ul
OM115559-20ul
20ul
1~2 Week
Product Profile
Product Name Rabbit anti-GSN polyclonal antibody - C-terminal region
Antibody Type Primary Antibodies
Antigen Alias DKFZp313L0718, ADF, AGEL
Immunogen The immunogen for anti-GSN antibody: synthetic peptide directed towards the C terminal of human GSN
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WBIHC
WB:1:500~1:2000
IHC:1:50~1:200
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity BovineDogGuinea PigHumanMousePigRatSheepZebra Fish
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol GSN
Gene Synonyms DKFZp313L0718
ADF
AGEL
Gene Full Name Gelsolin
Gene Summary GSN binds to the 'plus' ends of actin monomers and filaments to prevent monomer exchange. It is a calcium-regulated protein, which functions in both assembly and disassembly of actin filaments. Defects in the gene encoding GSN are a cause of familial amyloidosis Finnish type (FAF).The protein encoded by this gene binds to the 'plus' ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene.
Alternative Names DKFZp313L0718
ADF
AGEL
Molecular Weight(MW) 83kDa
Sequence 782 amino acids
Database Links
Entrez Gene 2934
SwissProt ID P06396
Protein Accession NP_000168
Application

Immunohistochemical

Paraffin embedded tonsil tissue, tested with an antibody Dilution of 5 ug/ml.

Western blot

Host: Rabbit Target Name: CHAD Sample Tissue: Human Adult Placenta Antibody Dilution: 1.0ug/ml

Western blot

Host: Rabbit Target Name: GNAS Sample Tissue: Human Fetal Heart Antibody Dilution: 1.0ug/ml

Western blot

GSN antibody - C-terminal region validated by WB using pFA fixed human tonsil tissue

Western blot

0.2-1 ug/mlPositive Control: MCF7 cell lysate
Application Notes WB:1:500~1:2000
IHC:1:50~1:200
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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